A Transient Closed-loop System for Autonomous Electrotherapy

A remarkable feature of modern integrated circuit technology is its ability to operate in a stable fashion, with almost perfect reliability, without physical or chemical change. Recently developed classes of electronic materials create an opportunity to engineer the opposite outcome, in the form of ‘transient’ devices that dissolve, disintegrate or otherwise disappear at triggered times or with controlled rates. Water-soluble transient electronics serve as the foundations for interesting applications in bioresorbable medical implants based on body chemistry. In my talk, I will present the foundational concepts in chemistry, materials science, and assembly processes of bioresorbable medical devices. Wireless body-integrated devices with closed-loop system designed for use in autonomous treatment of temporary bradycardia provide application example.

Dr. Yeon Sik Choi obtained his BS (2009) and MS (2011) degrees from Yonsei University, Korea in the Materials Science and Engineering Department. He spent 2011-2015 as a senior researcher in the Advanced Materials Development Team at LG Chem. Ltd. R&D Center, Korea, working on polymer nanocomposite for electronic devices. In 2019, he received a PhD under the guidance of Prof. Sohini Kar-Narayan, in the Materials Science and Metallurgy from University of Cambridge, UK, with support from the Cambridge Trust Scholarship. Currently, he works under Prof. John A. Rogers as a NIH K99 postdoctoral fellow in the Querrey Simpson Institute for Bioelectronics at Northwestern University, USA.

In 2021, Dr. Choi received the Pathway to Independence Award (K99/R00) from the National Institutes of Health (NIH). He is also the recipient of the IIN Outstanding Research Award (2021), the Baxter Young Investigator Award (2021), the Regeneron Prize for Creative Innovation (2021), the CSAR PhD Student Award (2019), the ABTA Doctoral Researcher Award (2018), and two best paper, three best poster awards. Dr. Choi’s works have received extensive global media coverage. One of his inventions - bioresorbable cardiac pacemaker - is exhibited as a permanent collection at the Thackray Museum of Medicine in Leeds (UK).

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